When I saw the previews for Fallout 4 I knew the first thing I needed was a change in the color of the HUD, it was an eyesore. Thank goodness they again included settings to change the color of your interface. These are simply settings to change the Pip-boy, VATS, and HUD color to the exact shade of amber that was used in New Vegas’ HUD by default, which was always my favorite:
Change the following in your Fallout4Prefs.ini (usually in Documents\my games\Fallout4):
The included file is just a copy of these instructions, for you to download, and possibly endorse me if you feel so inclined
P.S., If you want to decrease the intensity of the amber color, try increasing the Blue (B) values a bit.